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Article

Meta-analysis of cytochrome P-450 2C9 polymorphism and colorectal cancer risk.

PloS one - 1 Jan 2012

Liang Shuo, Hu Jinsong, Hu Jingsong, Cao Weijun, Cai Sanjun

Abstract excerpt

BACKGROUND: CYP2C9 encodes a member of the cytochrome P450 superfamily of enzymes which play a central role in activating and detoxifying many carcinogens and endogenous compounds thought to be involved in the development of colorectal cancer (CRC). In the past decade, the relationship between CYP2C9 common polymorphisms (R144C and I359L) and CRC has been reported in various ethnic groups; however, these studies...

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Identifiers

PMID: 23145098
DOI: 10.1371/journal.pone.0049134
PMCID: PMC3492323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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