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Article

Current evidence on the relationship between three polymorphisms in the CYP1A2 gene and the risk of cancer.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Nov 2013

Zhenzhen Li, Xianghua Liu, Ning Sun, Zhan Guo, Chuanchuan Ren, Jie Li

Abstract excerpt

CYP1A2 is an important cytochrome P450 enzyme that is involved in the metabolism of many clinical drugs and activation of some precarcinogens. Functional CYP1A2 polymorphisms are considered to exert significant effects on the risk of cancer, but the conclusions are inconsistent. Three commonly studied CYP1A2 polymorphisms, namely rs762551 (A>C), rs2069514 (G>A), and rs3569413 (T>delT), were selected to explore...

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PMID: 23462460
DOI: 10.1097/CEJ.0b013e32835f3bd2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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