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Article

Association between CYP2E1 polymorphisms and colorectal cancer risk: a systematic review and meta-analysis.

Scientific reports - 23 Nov 2022

Sharzehan Mohamad Ayub Khan, Sito Hilary, Abdullah Noraidatulakma, Alexiou Athanasios, Papadakis Marios, Jamal Rahman, Tan Shing Cheng

Abstract excerpt

CYP2E1 encodes an enzyme that participates in the activation of several carcinogenic substances. Thus, numerous studies have investigated the association between CYP2E1 polymorphisms and colorectal cancer (CRC) risk, but inconclusive results have been obtained. We performed a meta-analysis to precisely evaluate the relationship of CYP2E1 rs2031920, rs3813867, and rs6413432 polymorphisms with the susceptibility to...

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Identifiers

PMID: 36418904
DOI: 10.1038/s41598-022-24398-w
PMCID: PMC9684517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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