Article
Systems genetics of hepatocellular damage in vivo and in vitro: identification of a critical network on chromosome 11 in mouse.
Physiological genomics - 16 Oct 2013
Liebe Roman, Hall Rabea A, Williams Robert W, Dooley Steven, Lammert Frank
Abstract excerpt
Quantitative trait locus (QTL) mapping is a powerful method to find modifier loci that influence disease risk and progression without prior knowledge of underlying genetic mechanisms. The aim of this study is to identify gene loci that contribute to individual differences in liver fibrosis following chronic liver damage. For this purpose, we carried out a mapping study across a panel of 21 BXD recombinant inbred...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
