Article
Liver fibrosis: from animal models to mapping of human risk variants.
Best practice & research. Clinical gastroenterology - 1 Oct 2010
Weber Susanne N, Wasmuth Hermann E
Abstract excerpt
Liver fibrosis is the sequel of chronic liver diseases and the main reason for increased mortality in affected patients. The extent of liver fibrosis displays great interindividual variation, even after controlling for exogenous factors. Thus, host genetic factors are considered to play an important role in the process of liver scarring. From a genetic perspective, liver fibrosis is a complex trait with many...
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