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Article

A relationship between the aggregation rates of α-synuclein variants and the β-sheet populations in their monomeric forms.

The journal of physical chemistry. B - 19 Sept 2013

Camilloni Carlo, Vendruscolo Michele

Abstract excerpt

Intrinsically disordered proteins constitute a significant part of the human proteome and carry out a wide range of different functions, including in particular signaling and regulation. Several of these proteins are vulnerable to aggregation, and their aberrant assemblies have been associated with a variety of neurodegenerative and systemic diseases. It remains unclear, however, the extent to which the...

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PMID: 23941114
DOI: 10.1021/jp405614j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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