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Article

Somatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations.

Endocrine-related cancer - 1 Oct 2013

Jaffrain-Rea Marie-Lise, Rotondi Sandra, Turchi Annarita, Occhi Gianluca, Barlier Anne, Peverelli Erika, Rostomyan Lilya, Defilles Céline, Angelini Mariolina, Oliva Maria-Antonietta, Ceccato Filippo, Maiorani Orlando, Daly Adrian F, Esposito Vincenzo, Buttarelli Francesca, Figarella-Branger Dominique, Giangaspero Felice, Spada Anna, Scaroni Carla, Alesse Edoardo, Beckers Albert

Abstract excerpt

Germline aryl hydrocarbon receptor interacting protein (AIP) gene mutations confer a predisposition to pituitary adenoma (PA), predominantly GH-secreting (GH-PA). As recent data suggest a role for AIP in the pathogenesis of sporadic GH-PA and their response to somatostatin analogues (SSA), the expression of AIP and its partner, aryl hydrocarbon receptor (AHR), was determined by semiquantitative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23940012
DOI: 10.1530/ERC-12-0322

Genes

AIP
AHR
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations.PMID 23940012Read ↗

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