Article
Molecular genetics of the aip gene in familial pituitary tumorigenesis.
Progress in brain research - 1 Jan 2010
Tahir Asil, Chahal Harvinder S, Korbonits Márta
Abstract excerpt
Pituitary adenomas usually occur as sporadic tumors, but familial cases are now increasingly identified. As opposed to multiple endocrine neoplasia type 1 and Carney complex, in familial isolated pituitary adenoma (FIPA) syndrome no other disease is associated with the familial occurrence of pituitary adenomas. It is an autosomal dominant disease with incomplete variable penetrance. Approximately 20% of patients...
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