Article
NOTCH1 gain of function in germ cells causes failure of spermatogenesis in male mice.
PloS one - 1 Jan 2013
Huang Zaohua, Rivas Bryan, Agoulnik Alexander I
Abstract excerpt
NOTCH1 is a member of the NOTCH receptor family, a group of single-pass trans-membrane receptors. NOTCH signaling is highly conserved in evolution and mediates communication between adjacent cells. NOTCH receptors have been implicated in cell fate determination, as well as maintenance and differe...
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