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Article

Dicer Is Required for Haploid Male Germ Cell Differentiation in Mice

16 Sept 2011

Abstract excerpt

BACKGROUND: The RNase III endonuclease Dicer is an important regulator of gene expression that processes microRNAs (miRNAs) and small interfering RNAs (siRNAs). The best-characterized function of miRNAs is gene repression at the post-transcriptional level through the pairing with mRNAs of protein-encoding genes. Small RNAs can also act at the transcriptional level by controlling the epigenetic status of...

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PMID: 21949761
DOI: 10.1371/journal.pone.0024821

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