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Article

Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice.

Cell death & disease - 23 Jan 2018

Wang Hong, Yuan Qingqing, Niu Minghui, Zhang Wenhui, Wen Liping, Fu Hongyong, Zhou Fan, He Zuping

Abstract excerpt

Infertility affects 10-15% of couples worldwide, and male factors account for 50%. Spermatogenesis is precisely regulated by genetic factors, and the mutations of genes result in abnormal spermatogenesis and eventual male infertility. The aim of this study was to explore the role and transcriptional regulation of P63 in the apoptosis and mouse spermatogenesis. P63 protein was decreased in male germ cells of...

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Identifiers

PMID: 29362488
DOI: 10.1038/s41419-017-0046-z
PMCID: PMC5833356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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