Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls.

PloS one - 1 Jan 2013

Lamontagne Maxime, Couture Christian, Postma Dirkje S, Timens Wim, Sin Don D, Paré Peter D, Hogg James C, Nickle David, Laviolette Michel, Bossé Yohan

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of mortality worldwide. Recent genome-wide association studies (GWAS) have identified robust susceptibility loci associated with COPD. However, the mechanisms mediating the risk conferred by these loci remain to be found. The goal of this study was to identify causal genes/variants within susceptibility loci associated with COPD. In the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 19

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 4

Share to Gene Expression

Share to Linkage Disequilibrium

Share to Pulmonary Disease, Chronic Obstructive

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 23936167
DOI: 10.1371/journal.pone.0070220
PMCID: PMC3728203

Genes

EGLN2
HHIP
MIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls.PMID 23936167Read ↗

COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression.Semantic proximity Read ↗

Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associationsSemantic proximity Read ↗

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.Semantic proximity Read ↗

Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci.Semantic proximity Read ↗

Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations.Semantic proximity Read ↗

Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.Semantic proximity Read ↗

Integration of SNP Disease Association, eQTL, and Enrichment Analyses to Identify Risk SNPs and Susceptibility Genes in Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.Semantic proximity Read ↗

Expanded genetic landscape of chronic obstructive pulmonary disease reveals heterogeneous cell type and phenotype associationsSemantic proximity Read ↗

Lung eQTLs to help reveal the molecular underpinnings of asthma.Semantic proximity Read ↗

Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD Risk Locus 19q13.2Semantic proximity Read ↗

Transcriptome-wide association study reveals candidate causal genes for lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.