Article
Functional characterization of stromal osteopontin in melanoma progression and metastasis.
PloS one - 1 Jan 2013
Kumar Santosh, Sharma Priyanka, Kumar Dhiraj, Chakraborty Goutam, Gorain Mahadeo, Kundu Gopal C
Abstract excerpt
BACKGROUND: Recent studies demonstrated that not only tumor derived- but stroma derived factors play crucial role in cancer development. Osteopontin (OPN) is a secreted non-collagenous, sialic acid rich, chemokine-like phosphoglycoprotein that facilitates cell-matrix interactions and promotes tum...
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