Article
Mechanisms of protein sequence divergence and incompatibility.
PLoS genetics - 1 Jan 2013
Wellner Alon, Raitses Gurevich Maria, Tawfik Dan S
Abstract excerpt
Alignments of orthologous protein sequences convey a complex picture. Some positions are utterly conserved whilst others have diverged to variable degrees. Amongst the latter, many are non-exchangeable between extant sequences. How do functionally critical and highly conserved residues diverge? W...
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