Article
Protein evolution: causes of trends in amino-acid gain and loss.
Nature - 24 Aug 2006
Hurst Laurence D, Feil Edward J, Rocha Eduardo P C
Abstract excerpt
Understanding how proteins evolve is important for determining the molecular basis of adaptation, for inferring phylogenies and for engineering novel proteins. It has been suggested that some amino acids were incorporated into the genetic code more recently than others and, after comparing pairs of closely related genomes, Jordan et al. report that 'recent' amino acids are becoming more common. They argue that...
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