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Article

The role of Polycomb-group response elements in regulation of engrailed transcription in Drosophila.

Development (Cambridge, England) - 1 Feb 2008

DeVido Sarah K, Kwon Deborah, Brown J Lesley, Kassis Judith A

Abstract excerpt

Polycomb group proteins are required for long-term repression of many genes in Drosophila and all metazoans. In Drosophila, DNA fragments called Polycomb-group response elements (PREs) have been identified that mediate the action of Polycomb-group proteins. Previous studies have shown that a 2 kb fragment located from -2.4 kb to -395 bp upstream of the Drosophila engrailed promoter contains a multipartite PRE...

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Share to Embryo, Nonmammalian
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Silencer Elements, Transcriptional

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Source

Identifiers

PMID: 18199580
DOI: 10.1242/dev.014779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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