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Article

First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum.

Genome biology - 28 Sept 2011

Yu Willie, Chan-On Waraporn, Teo Melissa, Ong Choon Kiat, Cutcutache Ioana, Allen George E, Wong Bernice, Myint Swe Swe, Lim Kiat Hon, Voorhoeve P Mathijs, Rozen Steve, Soo Khee Chee, Tan Patrick, Teh Bin Tean

Abstract excerpt

BACKGROUND: Well differentiated papillary mesothelioma of the peritoneum (WDPMP) is a rare variant of epithelial mesothelioma of low malignancy potential, usually found in women with no history of asbestos exposure. In this study, we perform the first exome sequencing of WDPMP. RESULTS: WDPMP exome sequencing reveals the first somatic mutation of E2F1, R166H, to be identified in human cancer. The location is in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21955916
DOI: 10.1186/gb-2011-12-9-r96
PMCID: PMC3308059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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