Article
Development of a dendritic cell vaccine encoding multiple cytotoxic T lymphocyte epitopes targeting hepatitis C virus.
International journal of molecular medicine - 1 Oct 2013
Zhou Yun, Zhao Futao, Chen Lin, Ma Li, Wang Yu, He Yu, Ma Zhiyuan, Liu Haili, Guo Yonghong, Zhang Ying, Yao Zhiqiang, Hao Chunqiu, Jia Zhansheng
Abstract excerpt
The aim of the present study was to develop a dendritic cell (DC) vaccine encoding hepatitis C virus (HCV) multiple cytotoxic T lymphocyte (CTL) epitopes that can stimulate T cell responses in vitro, and can be used for immunization in vivo. DCs were infected with recombinant replication-defectiv...
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