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Vaccine Development T-cell (MHC-I) Epitopes Identification Against the Indian HCV Genotype: An Approach Based on Immunoinformatic.

Molecular biotechnology - 1 Feb 2026

Iyyanar Sridevi, Ravi Sai Nandhini

Abstract excerpt

Hepatitis C virus (HCV) infects approximately 58 million individuals worldwide, often progressing to chronic liver disease, cirrhosis, and hepatocellular carcinoma. The viral envelope glycoproteins E1 and E2 are critical for HCV entry and serve as primary targets for neutralizing antibodies. Recent advancements in cryo-electron tomography have provided high-resolution structures (3.5 Å) of the E1E2 heterodimer,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39994132
DOI: 10.1007/s12033-025-01398-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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