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Article

Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study.

International journal of obesity (2005) - 1 Mar 2021

Beyer Frauke, Zhang Rui, Scholz Markus, Wirkner Kerstin, Loeffler Markus, Stumvoll Michael, Villringer Arno, Witte A Veronica

Abstract excerpt

BACKGROUND: Obesity is of complex origin, involving genetic and neurobehavioral factors. Genetic polymorphisms may increase the risk for developing obesity by modulating dopamine-dependent behaviors, such as reward processing. Yet, few studies have investigated the association of obesity, related genetic variants, and structural connectivity of the dopaminergic reward network. METHODS: We analyzed 347...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33100325
DOI: 10.1038/s41366-020-00702-4
PMCID: PMC7906899

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