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Article

Depressive disorder moderates the effect of the FTO gene on body mass index.

Molecular psychiatry - 1 Jun 2012

Rivera M, Cohen-Woods S, Kapur K, Breen G, Ng M Y, Butler A W, Craddock N, Gill M, Korszun A, Maier W, Mors O, Owen M J, Preisig M, Bergmann S, Tozzi F, Rice J, Rietschel M, Rucker J, Schosser A, Aitchison K J, Uher R, Craig I W, Lewis C M, Farmer A E, McGuffin P

Abstract excerpt

There is evidence that obesity-related disorders are increased among people with depression. Variation in the FTO (fat mass and obesity associated) gene has been shown to contribute to common forms of human obesity. This study aimed to investigate the genetic influence of polymorphisms in FTO in relation to body mass index (BMI) in two independent samples of major depressive disorder (MDD) cases and controls. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21502950
DOI: 10.1038/mp.2011.45

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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