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Article

Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study.

The Journal of clinical psychiatry - 1 Dec 2015

Samaan Zainab, Lee Yvonne K, Gerstein Hertzel C, Engert James C, Bosch Jackie, Mohan Viswanathan, Diaz Rafael, Yusuf Salim, Anand Sonia S, Meyre David

Abstract excerpt

OBJECTIVE: Observational studies have shown a positive association between obesity (body mass index [BMI] ≥ 30 kg/m2) and depression. Around 120 obesity-associated loci have been identified, but genetic variants associated with depression remain elusive. Recently, our team reported that the fat mass and obesity-associated (FTO) gene rs9939609 obesity-risk variant is paradoxically inversely associated with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26717541
DOI: 10.4088/JCP.14m09720

Genes

FTO
TAL1
BDNF
CDKAL1
GIPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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