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Article

Association of myasthenia gravis with polymorphisms in the gene of histamine N-methyltransferase.

Human immunology - 1 Dec 2013

Kellermayer Blanka, Polgar Noemi, Pal Jozsef, Banati Miklos, Maasz Anita, Kisfali Peter, Hosszu Zsolt, Juhasz Annamaria, Jensen Henrik Boye, Tordai Attila, Rozsa Csilla, Melegh Bela, Illes Zsolt

Abstract excerpt

INTRODUCTION: Histamine N-methyltransferase (HNMT) is the main metabolizing enzyme of histamine. Histamine modulates immune responses and plays a role in the pathogenesis of autoimmune disorders. METHODS: The non-synonymous HNMT C314T polymorphism and the A939G single-nucleotide polymorphism (SNP) influencing HNMT mRNA stability were genotyped in 213 patients with myasthenia gravis (MG) and 342 healthy controls....

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Identifiers

PMID: 23932992
DOI: 10.1016/j.humimm.2013.07.016

Genes

HNMT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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