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Article

Genetic heterogeneity within the HLA region in three distinct clinical subgroups of myasthenia gravis.

Clinical immunology (Orlando, Fla.) - 1 May 2016

Saruhan-Direskeneli Güher, Hughes Travis, Yilmaz Vuslat, Durmus Hacer, Adler Adam, Alahgholi-Hajibehzad Mahdi, Aysal Fikret, Yentür Sibel P, Akalin Mehmet Ali, Dogan Oner, Marx Alexander, Gülsen-Parman Yesim, Oflazer Piraye, Deymeer Feza, Sawalha Amr H

Abstract excerpt

This study aims to investigate genetic susceptibility to early-onset and late-onset anti-acetylcholine receptor antibody positive myasthenia gravis (EOMG and LOMG) and anti-muscle specific kinase antibody positive MG (MuSK-MG) at genome-wide level in a single population. Using a custom-designed array and imputing additional variants and the classical HLA alleles in 398 patients, we detected distinct associations....

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Identifiers

PMID: 27181991
DOI: 10.1016/j.clim.2016.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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