Article
Single nucleotide polymorphisms and haplotypes of histamine N-methyltransferase in patients with gastric ulcer.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Sept 2004
Chen G-L, Zhu B, Nie W-P, Xu Z-H, Tan Z-R, Zhou G, Liu J, Wang W, Zhou H-H
Abstract excerpt
INTRODUCTION: Histamine plays a crucial role in the regulation of gastric acid secretion, which is involved in the pathogenesis of peptic ulcer. Histamine N-methyltransferase (HNMT) is the major metabolizing enzyme for histamine inactivation in human stomach. OBJECTIVE: This study aims to determine whether there exists a relationship between HNMT gene polymorphisms and the risk for gastric ulcer (GU). METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.