Article
Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children.
Pharmacotherapy - 1 Dec 2008
Kennedy Mary Jayne, Loehle Jennifer A, Griffin Angela R, Doll Mark A, Kearns Gregory L, Sullivan Janice E, Hein David W
Abstract excerpt
STUDY OBJECTIVE: To investigate potential associations between the histamine N-methyltransferase (HNMT) gene, HNMT, C314T (Thr105Ile) polymorphism and atopic dermatitis in a cohort of Caucasian children. DESIGN: Prospective, multicenter, genotype-association study. SETTING: Four academic, tertiary care medical centers within the Pediatric Pharmacology Research Unit network. PARTICIPANTS: Two hundred forty-nine...
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