Article
Histamine N-methyltransferase 939A>G polymorphism affects mRNA stability in patients with acetylsalicylic acid-intolerant chronic urticaria.
Allergy - 1 Feb 2009
Kim S-H, Kang Y-M, Kim S-H, Cho B-Y, Ye Y-M, Hur G-Y, Park H-S
Abstract excerpt
BACKGROUND: Histamine plays an important role in allergic inflammation. Histamine levels are regulated by histamine N-methyltransferase (HNMT). OBJECTIVE: To investigate the functional variability of HNMT gene in relation to genetic polymorphisms in patients with aspirin intolerant chronic urticaria (AICU). METHODS: Two single-nucleotide polymorphisms of the HNMT gene (314C>T, 939A>G) were genotyped in chronic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
