Article
Strong allelic selection in the course of brother x sister matings in mice.
The Journal of heredity - 1 Jan 2000
Motta R, Spach C
Abstract excerpt
A set of 36 recombinant congenic mouse strains, resulting from crosses between B10.D2 and DBA/2, was created. During the backcross phase, animals were selected for their sensitivity to the graft-versus-host reaction induced by a B10.D2 hematopoietic cell transplant after irradiation. The progress of inbreeding was followed throughout the brother x sister phase by determining the allelic form of 14 genetic...
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