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Article

Induction of mixed vs full chimerism to potentiate GVL effects after bone-marrow transplantation.

Methods in molecular medicine - 1 Jan 2005

Mapara Markus Y, Sykes Megan

Abstract excerpt

Graft-vs-host (GVH) alloresponses mediated by delayed donor lymphocyte infusions (DLI) can occur in the absence of GVHD (graft-vs-host disease). These GVH responses are confined to the lymphohematopoietic system and mediate graft-vs-leukemia (GVL) reactions without causing GVHD. Although interaction of donor T-cells with host-derived antigen-presenting cells (APC) is central to the development of GVHD, we were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15585939
DOI: 10.1385/1-59259-862-5:469

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Induction of mixed vs full chimerism to potentiate GVL effects after bone-marrow transplantation.PMID 15585939Read ↗

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