Article
Alteration of the T cell repertoire after bone marrow transplantation.
Bone marrow transplantation - 1 Jan 1994
Villers D, Milpied N, Gaschet J, Davodeau F, Hallet M M, Bonneville M, Vié H
Abstract excerpt
We investigated T cell receptor (TCR) alpha/beta and gamma/delta repertoire reconstitution after autologous and allogeneic bone marrow transplantation (BMT) in humans using 13 monoclonal antibodies directed at constant and variable regions of the TCR. The TCR gamma/delta repertoire was studied kinetically during the first month and then 1 year post-BMT whereas alpha/beta peripheral blood T lymphocytes (PBTL) were...
Read the complete abstract on PubMedTopics
- Adolescent
- Adult
- Bone Marrow Transplantation
- Child
- Female
- Gene Expression
- Humans
