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Telomerase Activity and Telomere Length in Male Germ Cells

8 Jan 2015

Abstract excerpt

Telomeres are located at the outermost ends of all eukaryotic chromosomes and provide for the maintenance of genomic stability and integrity during the life span of organisms. The length of telomeres shortens due to each round of DNA replication, genotoxic insults, and/or reactive oxygen species. To counteract this shortening, certain types of cells, including stem cells, male/female germline cells, granulosa...

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PMID: 25568305
DOI: 10.1095/biolreprod.114.124008

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