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Article

Rines E3 ubiquitin ligase regulates MAO-A levels and emotional responses.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Aug 2013

Kabayama Miyuki, Sakoori Kazuto, Yamada Kazuyuki, Ornthanalai Veravej G, Ota Maya, Morimura Naoko, Katayama Kei-ichi, Murphy Niall P, Aruga Jun

Abstract excerpt

Monoamine oxidase A (MAO-A), the catabolic enzyme of norepinephrine and serotonin, plays a critical role in emotional and social behavior. However, the control and impact of endogenous MAO-A levels in the brain remains unknown. Here we show that the RING finger-type E3 ubiquitin ligase Rines/RNF1...

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Identifiers

PMID: 23926250
DOI: 10.1523/JNEUROSCI.5717-12.2013
PMCID: PMC6619730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23926250-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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