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Article

Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence.

International review of neurobiology - 1 Jan 2011

Bortolato Marco, Shih Jean C

Abstract excerpt

Monoamine oxidase (MAO) isoenzymes A and B are mitochondrial-bound proteins, catalyzing the oxidative deamination of monoamine neurotransmitters as well as xenobiotic amines. Although they derive from a common ancestral progenitor gene, are located at X-chromosome and display 70% structural identity, their substrate preference, regional distribution, and physiological role are divergent. In fact, while MAO-A has...

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Identifiers

PMID: 21971001
DOI: 10.1016/B978-0-12-386467-3.00002-9
PMCID: PMC3371272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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