Article
Regulation of impulsive and aggressive behaviours by a novel lncRNA.
Molecular psychiatry - 1 Aug 2021
Labonté Benoit, Abdallah Khaled, Maussion Gilles, Yerko Volodymyr, Yang Jennie, Bittar Thibault, Quessy Francis, Golden Sam A, Navarro Luis, Checknita Dave, Gigek Carolina, Lopez Juan Pablo, Neve Rachael L, Russo Scott J, Tremblay Richard E, Côté Gilles, Meaney Michael J, Mechawar Naguib, Nestler Eric J, Turecki Gustavo
Abstract excerpt
High impulsive and aggressive traits associate with poor behavioural self-control. Despite their importance in predicting behavioural negative outcomes including suicide, the molecular mechanisms underlying the expression of impulsive and aggressive traits remain poorly understood. Here, we identified and characterized a novel long noncoding RNA (lncRNA), acting as a regulator of the monoamine oxidase A (MAOA)...
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