Article
Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.
Thorax - 1 Jan 2014
van den Berge Maarten, Steiling Katrina, Timens Wim, Hiemstra Pieter S, Sterk Peter J, Heijink Irene H, Liu Gang, Alekseyev Yuriy O, Lenburg Marc E, Spira Avrum, Postma Dirkje S
Abstract excerpt
BACKGROUND: A core feature of chronic obstructive pulmonary disease (COPD) is the accelerated decline in forced expiratory volume in one second (FEV1). The recent Groningen and Leiden Universities study of Corticosteroids in Obstructive Lung Disease (GLUCOLD) study suggested that particular pheno...
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