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Article

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.

Thorax - 1 Jan 2014

van den Berge Maarten, Steiling Katrina, Timens Wim, Hiemstra Pieter S, Sterk Peter J, Heijink Irene H, Liu Gang, Alekseyev Yuriy O, Lenburg Marc E, Spira Avrum, Postma Dirkje S

Abstract excerpt

BACKGROUND: A core feature of chronic obstructive pulmonary disease (COPD) is the accelerated decline in forced expiratory volume in one second (FEV1). The recent Groningen and Leiden Universities study of Corticosteroids in Obstructive Lung Disease (GLUCOLD) study suggested that particular phenotypes of COPD benefit from fluticasone±salmeterol by reducing the rate of FEV1 decline, yet the underlying mechanisms...

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Identifiers

PMID: 23925644
DOI: 10.1136/thoraxjnl-2012-202878
PMCID: PMC3888587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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