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Article

Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

15 Oct 2020

Abstract excerpt

-agonist (LABA) treatment on both lung function measures of hyperinflation, and the nasal epithelial gene-expression profile in severe COPD. 117 patients were screened and 60 COPD patients entered a 1-month run-in period on low-dose ICS/LABA budesonide/formoterol (BUD/F) 200/6 one inhalation b.i.d. Patients were then randomly assigned to 3-month treatment with either a high dose BDP/F 100/6 two inhalations b.i.d....

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PMID: 33060632
DOI: 10.1038/s41598-020-72551-0

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