Article

Molecular Determinants of Lung Function Decline: A Multi- Level Analysis of Gene Expression

2025-08-19

Abstract excerpt

<title>Abstract</title> <p> Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive lung function decline, commonly measured by forced expiratory volume in one second (FEV <sub>1</sub> ). Uncovering the genetic basis of FEV <sub>1</sub> decline is essential for understanding COPD pathophysiology and for developing therapies. We hypothesized that gene expression patterns in in...

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Literature Corpus work: 89b1def9-3a27-5f05-91fa-cfd132dfc095
DOI: 10.21203/rs.3.rs-7292685/v1

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