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Article

HeLa nucleic acid contamination in the cancer genome atlas leads to the misidentification of human papillomavirus 18.

Journal of virology - 1 Apr 2015

Cantalupo Paul G, Katz Joshua P, Pipas James M

Abstract excerpt

UNLABELLED: We searched The Cancer Genome Atlas (TCGA) database for viruses by comparing non-human reads present in transcriptome sequencing (RNA-Seq) and whole-exome sequencing (WXS) data to viral sequence databases. Human papillomavirus 18 (HPV18) is an etiologic agent of cervical cancer, and as expected, we found robust expression of HPV18 genes in cervical cancer samples. In agreement with previous studies,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25631090
DOI: 10.1128/JVI.03365-14
PMCID: PMC4442357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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