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A ferrofluid-based homogeneous assay for highly sensitive and selective detection of single-nucleotide polymorphisms.

Chemical communications (Cambridge, England) - 21 Sept 2013

Shen Wei, Lim Cai Le, Gao Zhiqiang

Abstract excerpt

A simple and low-cost colorimetric assay utilizing ferrofluidic nanoparticulate probes (FNPs) and a ligase for single-nucleotide polymorphism genotyping is described. Excellent sensitivity and selectivity were accomplished through the engagement of the FNPs and a ligase chain reaction.

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Biological Assay
Colorimetry
Ligases
Limit of Detection
Magnetics
Nanoparticles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 23923128
DOI: 10.1039/c3cc43281e

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