Article
Multiplex single-nucleotide polymorphism typing by nanoparticle-coupled DNA-templated reactions.
Journal of the American Chemical Society - 26 Aug 2009
Xue Xuejia, Xu Wei, Wang Feng, Liu Xiaogang
Abstract excerpt
A novel chip-based detection approach for single-nucleotide polymorphism (SNP) typing based on nanoparticle-coupled DNA-templated ligation reactions is reported. In contrast to conventional methods or recently developed techniques, this approach does not need costly instrumentation and complex st...
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