Article
The mouse formin (Fmn) gene: abundant circular RNA transcripts and gene-targeted deletion analysis.
Molecular medicine (Cambridge, Mass.) - 1 Sept 1998
Chao C W, Chan D C, Kuo A, Leder P
Abstract excerpt
BACKGROUND: Mutations in the mouse formin (Fmn) gene result in limb deformities and incompletely penetrant renal aplasia. A molecular genetic approach was taken to characterize novel circular RNAs from the Fmn gene and to understand the developmental effects of gene-targeted mutations. MATERIALS AND METHODS: RT-PCR and ribonuclease protection analyses were done to characterize the circular RNA transcripts arising...
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