Article
The mouse formin (Fmn) gene: abundant circular RNA transcripts and gene-targeted deletion analysis.
Molecular medicine (Cambridge, Mass.) - 1 Sept 1998
Chao C W, Chan D C, Kuo A, Leder P
Abstract excerpt
BACKGROUND: Mutations in the mouse formin (Fmn) gene result in limb deformities and incompletely penetrant renal aplasia. A molecular genetic approach was taken to characterize novel circular RNAs from the Fmn gene and to understand the developmental effects of gene-targeted mutations. MATERIALS...
Topics
- Animals
- Chimera
- DNA, Complementary
- Exons
- Female
- Fetal Proteins
- Formins
- Genotype
- Kidney
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mice, Neurologic Mutants
- Mice, Transgenic
- Microfilament Proteins
- Nuclear Proteins
- RNA