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Article

Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.

Nucleic acids research - 1 Oct 2013

Sharma Sunny, Yang Jun, Watzinger Peter, Kötter Peter, Entian Karl-Dieter

Abstract excerpt

Yeast 25S rRNA was reported to contain a single cytosine methylation (m(5)C). In the present study using a combination of RP-HPLC, mung bean nuclease assay and rRNA mutagenesis, we discovered that instead of one, yeast contains two m(5)C residues at position 2278 and 2870. Furthermore, we identified and characterized two putative methyltransferases, Rcm1 and Nop2 to be responsible for these two cytosine...

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Identifiers

PMID: 23913415
DOI: 10.1093/nar/gkt679
PMCID: PMC3799443

Genes

NSUN5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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