Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors.

Journal of proteomics - 8 Oct 2013

Schweppe Devin K, Rigas James R, Gerber Scott A

Abstract excerpt

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. Within the molecular scope of NCSLC, a complex landscape of dysregulated cellular signaling has emerged, defined largely by mutations in select mediators of signal transduction, including the epidermal growth factor receptor (EGFR) and anaplastic lymphoma (ALK) kinases. Consequently, these mutant kinases become...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Arginine
Share to Extracellular Signal-Regulated MAP Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isotope Labeling

Share to Lysine

Share to Phosphoproteins

Share to Proteome

Share to Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 23911959
DOI: 10.1016/j.jprot.2013.07.023
PMCID: PMC3825743

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors.PMID 23911959Read ↗

The Role of Proteomics and Phosphoproteomics in the Discovery of Therapeutic Targets and Biomarkers in Acquired EGFR-TKI-Resistant Non-Small Cell Lung Cancer.Semantic proximity Read ↗

Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879VSemantic proximity Read ↗

Phosphoproteomics Identifies Oncogenic Ras Signaling Targets and Their Involvement in Lung AdenocarcinomasSemantic proximity Read ↗

Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling.Semantic proximity Read ↗

Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS.Semantic proximity Read ↗

A predictive phosphorylation signature of lung cancer.Semantic proximity Read ↗

Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer.Semantic proximity Read ↗

Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression.Semantic proximity Read ↗

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Semantic proximity Read ↗

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma.Semantic proximity Read ↗

Comprehensive transcriptome, miRNA and kinome profiling and its clinical translation for personalized lung cancer therapySemantic proximity Read ↗

Phosphoproteomics of extracellular vesicles integrated with multiomics analysis reveals novel kinase networks for lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.