Article
Fitness of drug-resistant malaria parasites.
Acta tropica - 1 Jun 2005
Walliker David, Hunt Paul, Babiker Hamza
Abstract excerpt
Drug-resistant mutant forms of an organism are likely to be less fit than their wild-type strains in the absence of selection. Experimental work on prokaryotic organisms suggests that this is the case, but that compensatory mutations may occur which restore the fitness of mutants to that of sensi...
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