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Article

Virulence, drug sensitivity and transmission success in the rodent malaria, Plasmodium chabaudi.

Proceedings. Biological sciences - 22 Nov 2012

Schneider Petra, Bell Andrew S, Sim Derek G, O'Donnell Aidan J, Blanford Simon, Paaijmans Krijn P, Read Andrew F, Reece Sarah E

Abstract excerpt

Here, we test the hypothesis that virulent malaria parasites are less susceptible to drug treatment than less virulent parasites. If true, drug treatment might promote the evolution of more virulent parasites (defined here as those doing more harm to hosts). Drug-resistance mechanisms that protect parasites through interactions with drug molecules at the sub-cellular level are well known. However, parasite...

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Identifiers

PMID: 23015626
DOI: 10.1098/rspb.2012.1792
PMCID: PMC3479731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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