Article
Prevalence of drug resistance associated mutations in Plasmodium vivax against sulphadoxine-pyrimethamine in southern Pakistan.
Malaria journal - 26 Jul 2013
Raza Afsheen, Ghanchi Najia K, Khan Muhammad Shahzeb, Beg Mohammad Asim
Abstract excerpt
BACKGROUND: In Pakistan, Plasmodium vivax and Plasmodium falciparum co-exist and usage of sulphadoxine-pyrimethamine (SP) against P. falciparum exposes P. vivax to the drug leading to generation of resistant alleles. The main aim of this study was to investigate frequency distribution of drug resistance associated mutations in pvdhfr, pvdhps genes and provide baseline molecular epidemiological data on...
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