Article
Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy.
Malaria journal - 2 Dec 2020
Madkhali Aymen M, Al-Mekhlafi Hesham M, Atroosh Wahib M, Ghzwani Ahmad Hassn, Zain Khalid Ammash, Abdulhaq Ahmed A, Ghailan Khalid Y, Anwar Alkhansa A, Eisa Zaki M
Abstract excerpt
BACKGROUND: Despite significant progress in eliminating malaria from the Kingdom of Saudi Arabia, the disease is still endemic in the southwestern region of the country. Artesunate plus sulfadoxine-pyrimethamine (AS + SP) has been used in Saudi Arabia since 2007 as a first-line treatment for uncomplicated Plasmodium falciparum malaria. This study aimed to investigate the prevalence of mutations associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.