Article
Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern Pakistan.
Malaria journal - 28 Jan 2011
Ghanchi Najia Karim, Ursing Johan, Beg Mohammad A, Veiga Maria I, Jafri Sana, Mårtensson Andreas
Abstract excerpt
BACKGROUND: Scarce data are available on Plasmodium falciparum anti-malarial drug resistance in Pakistan. The aim of this study was, therefore, to determine the prevalence of P. falciparum resistance associated polymorphisms in field isolates from southern Pakistan. METHODS: Blood samples from 24...
Topics
- Adolescent
- Adult
- Antimalarials
- Child
- Child, Preschool
- Chloroquine
- Dihydropteroate Synthase
- Drug Combinations
- Drug Resistance
- Female
- Gene Dosage
- Genes, Protozoan
- Humans
- Malaria, Falciparum
- Male
- Membrane Transport Proteins
- Multidrug Resistance-Associated Proteins
- Mutation