Article
A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan.
Malaria journal - 29 Aug 2013
Khattak Aamer A, Venkatesan Meera, Jacob Christopher G, Artimovich Elena M, Nadeem Muhammad F, Nighat Farida, Hombhanje Francis, Mita Toshihiro, Malik Salman A, Plowe Christopher V
Abstract excerpt
BACKGROUND: Few studies have been conducted in Pakistan to determine the efficacy of chloroquine and sulphadoxine-pyrimethamine (SP), which remain in use as treatment for Plasmodium vivax and in combination with artesunate to treat Plasmodium falciparum, respectively. In this study, samples from several sites across Pakistan were characterized to determine prevalence of molecular resistance markers in the P....
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