Article
Plasmodium vivax: prevalence of mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium vivax clinical isolates from Pakistan.
Experimental parasitology - 1 Jan 2011
Zakeri Sedigheh, Afsharpad Mandana, Ghasemi Faezeh, Raeisi Ahmad, Kakar Qutbuddin, Atta Hoda, Djadid Navid Dinparast
Abstract excerpt
The main aim of the present study was to investigate the frequency of SNPs-haplotypes of dhfr and dhps genes associated to sulfadoxine-pyrimethamine (SP) resistance in Plasmodium vivax clinical isolates circulating in a malaria endemic area, Pakistan. All 164 collected isolates were analyzed for SNPs-haplotypes at positions 13, 33, 57, 58, 61, 117 and 173 of pvdhfr and 383 and 553 of pvdhps genes using PCR-RFLP...
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